Proton magnetic resonance spectroscopy predicts concurrent chemoradiotherapy response and time-to-progression in high-grade gliomas after surgery
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proton Magnetic resonance spectroscopy in Differential Diagnosis of brain tuMors
The aim of the investigation was to assess the informativity of proton magnetic resonance spectroscopy (PMRS) data in differentiation of brain tumors and nonneoplastic diseases with similar signal characteristics on standard MRI scans, as well as glioma grade determination. Materials and Methods. We examined 45 patients aged from 25 to 56 years with suspected expansive process of brain using pr...
متن کاملRecent Application of Advanced MR Imaging to Predict Pseudoprogression in High-grade Glioma Patients
Pseudoprogression is regarded as a subacute form of treatment-related change with a reported incidence of 20-30%, occurring predominantly within the first three months after the completion of concurrent chemoradiotherapy (CCRT) in glioblastoma multiforme (GBM) patients. Occurrence of progressive lesions on conventional contrast-enhanced MR imaging may also accompany clinical deterioration, posi...
متن کاملLetter: Reoperation for recurrent high-grade glioma: does tumor genetics play a role?
To the Editor: We read with interest the systematic review published by Hervey-Jumper et al. The authors examined the role of reoperation in patients with World Health Organization grade III or IV recurrent gliomas. Of the 31 studies included in their analysis, 29 demonstrated survival benefit with reoperation for recurrence. Therefore, the authors concluded that, despite the selection bias, mo...
متن کاملنقش متابولیتها در تشخیص توده های مغزی با استفاده از طیف سنجی تشدید مغناطیس هسته ای و مقایسه غلظت آنها در بیماران تومورال با افراد سالم
Background and Aim: Brain tumors have remained as a significant cause of morbidity and mortality and are often refractory to treatment. The grading of brain tumor has an important implication in clinical management. Currently, magnetic resonance spectroscopy (MRS) is an important dimension in evaluating metabolites and grading brain tumors. The aim of this study is to evaluate metabolites in br...
متن کاملAmide Proton Transfer Imaging Allows Detection of Glioma Grades and Tumor Proliferation: Comparison with Ki-67 Expression and Proton MR Spectroscopy Imaging.
BACKGROUND AND PURPOSE Prognosis in glioma depends strongly on tumor grade and proliferation. In this prospective study of patients with untreated primary cerebral gliomas, we investigated whether amide proton transfer-weighted imaging could reveal tumor proliferation and reliably distinguish low-grade from high-grade gliomas compared with Ki-67 expression and proton MR spectroscopy imaging. ...
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